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Hypertension Medication and Skin Cancer Risk

By , On , In Skin Cancer Prevention
Female doctor using a blood pressure cuff, or sphygmomanometer, to measure a man's blood pressure.
High blood pressure often goes unnoticed without regular checks.

For people living with hypertension (high blood pressure), medication is a normal part of daily life. Recent research, however, has highlighted one topic that may be worth discussing with your doctor.

The risks associated with certain hypertension medications


Many individuals are not aware that they have hypertension.

Hydrochlorothiazide — a water-based diuretic commonly prescribed for high blood pressure — has been linked in observational studies to a higher risk of squamous cell carcinoma (SCC). This does not mean the medication causes SCC, but some research has shown an association, which has also been noted by the British Columbia College of Family Physicians.

Hypertension is common. About one in five Canadians lives with high blood pressure, often without knowing it. SCC is also common and typically appears on areas exposed to UV radiation, such as the head, neck, upper back, chest, and arms. While more research is needed, awareness of this possible link can help support informed conversations with your doctor.

What can you do?

Lifestyle factors such as physical activity, healthy eating, and stress management can support blood pressure control, although many people still require medication. If you use Hydrochlorothiazide, it may be helpful to review your treatment plan with your prescribing physician, particularly since observational studies suggest that longer-term use may carry more risk than shorter-term use.

If you have questions about SCC or your skin cancer risk, we’re here to help. Decisions about hypertension medications should always be discussed with your primary care provider or specialist.

For guidance on early detection, visit our skin screenings page:
https://kelownaskincancer.com/prevention/skin-screenings/

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