TOPICAL THERAPY
Targeted treatment applied to the skin.
Topical therapy may be recommended for certain early, non-invasive basal cell carcinomas, squamous cell carcinoma in situ (Bowen’s disease), and some precancerous skin changes. It works by applying medication directly to the affected area.
What is topical therapy?
Topical therapy involves applying a prescribed medication directly to the skin to target abnormal or precancerous cells. These medications belong to several well-established treatment classes used in Canada.
Types of topical therapy may include:
• Prescription creams designed to target abnormal or atypical skin cells
• Immune-modulating creams that help the body’s immune system respond to abnormal cells
• Light-activated creams used as part of photodynamic therapy
Topical therapy may be recommended for:
• Superficial basal cell carcinoma
• Squamous cell carcinoma in situ (Bowen’s disease)
• Actinic keratosis (pre-cancerous lesions)
How topical therapy works.
The medication
Your clinician will determine which topical approach is appropriate based on the diagnosis, the type of lesion being treated, and your individual health considerations. The medication is then applied to the area that requires treatment.
Topical therapy options.
Chemotherapy-based topical treatments
These prescription creams are applied directly to the skin to target abnormal or precancerous cells in a defined area. Treatment duration varies, and temporary redness or irritation is common during use. Your physician will determine whether this type of therapy is appropriate for you.
Photodynamic therapy (red-light activated)
Photodynamic therapy involves applying a light-sensitive cream in clinic, followed by activation with a specific light source. This approach targets abnormal cells in selected areas of the skin and is typically completed in cycles as recommended by your healthcare professional.
Clinic-applied treatments for actinic keratosis
Some topical treatments are applied in clinic and later activated with blue light. These treatments are often used for sun-damaged areas and are delivered under medical supervision.
The considerations of topical therapy.
Topical treatments are straightforward to use, but they can take several weeks to complete. Some people experience skin irritation during treatment, which may temporarily affect daily comfort.
Explore more treatment options.
At the Kelowna Skin Cancer Clinic, we offer several approaches to managing skin cancer. The best option depends on the type of lesion and your individual needs. Our team can help you understand what may be recommended and what to expect.